So You Can Keep It

A blocker consisting of locked nucleic acid antisense oligonucleotides, targeting the biomarker microRNA-181a-5p, is successful in protecting cartilage in spine and knee osteoarthritis, according to data published in the Annals of the Rheumatic Diseases.“This is important because there are cur... ... See more

This is BIG NEWS. Signifies that the FDA is considering indicating big pharma biologic biosimilars (bacterial protein made with human DNA) for what has been classically considered 'wear and tear arthritis' instead of 'inflammatory arthritis or RA'. Have been trying to point this out for over a decade. ... See more

CHICAGO — A recent study showed that tanezumab was well-tolerated and superior to placebo in patients with osteoarthritis. This analysis is the first completed clinical trial examining the investigational monoclonal antibody, which targets the nerve growth factor (NGF), since the FDA lifted it... ... See more

Fluctuating and persistent knee pain over 1 year predicts accelerated cartilage loss as well as an increased risk for incident and progressive radiographic osteoarthritis, according to data published in Arthritis Research & Therapy.“There have been data supporting the notion that knee pain... ... See more

HomeCirculation ResearchVol. 123, No. 7Mouse Models to Disentangle the Hallmarks of Human Aging Free AccessarticleDownload PDFAboutView Full TextView PDFSections ToolsAdd to favoritesDownload citationsTrack citationsPermissions ShareFacebookTwitterLinked InMendeleyGoogle+ ShareRedditDiggEmail Jump t... ... See more